Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LATS1 All Species: 18.18
Human Site: S602 Identified Species: 28.57
UniProt: O95835 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95835 NP_004681.1 1130 126870 S602 K S Y E N V D S G D K E K K Q
Chimpanzee Pan troglodytes XP_001173355 1130 126853 S602 K S Y E N V D S G D K E K K Q
Rhesus Macaque Macaca mulatta XP_001090321 809 89257 P354 P S H P A W V P A P A P A P A
Dog Lupus familis XP_534537 1097 121903 V589 I Q T S P V P V R K N S R D E
Cat Felis silvestris
Mouse Mus musculus Q8BYR2 1129 126167 S601 K S A D S G D S G D K E K K Q
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506215 1121 123969 G593 T H D N F D S G D R E K K Q I
Chicken Gallus gallus XP_419666 1136 127431 S608 K N Y E C V D S A D K E K K Q
Frog Xenopus laevis NP_001087838 1118 125984 T597 I T E K K Q I T T S P V P V R
Zebra Danio Brachydanio rerio NP_001018346 1068 120780 E588 F F M E Q H V E N I L K N H Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VA38 1105 122470 N591 P P A K Y N N N S S N T G A N
Honey Bee Apis mellifera XP_395146 1137 124999 S638 K G A G S S P S S Y K I K H Q
Nematode Worm Caenorhab. elegans Q2L6W9 476 55529 T21 T K D K A S C T R I S I E S Y
Sea Urchin Strong. purpuratus XP_795100 1199 133231 S678 L E S A S S D S Q P L E K S R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53894 756 86927 A301 Y Q S S V K Y A I E R N E R R
Red Bread Mold Neurospora crassa P38679 598 67999 N143 D K Y G P N A N N N Q K K C S
Conservation
Percent
Protein Identity: 100 99.6 35.8 50.9 N.A. 92.8 N.A. N.A. 80.8 85.2 74.7 63.1 N.A. 38.6 40.2 20.7 38
Protein Similarity: 100 99.8 44.7 63.4 N.A. 96.7 N.A. N.A. 87.1 92.1 83.4 73.7 N.A. 50.2 52.6 29.6 51.9
P-Site Identity: 100 100 6.6 6.6 N.A. 73.3 N.A. N.A. 6.6 80 0 13.3 N.A. 0 33.3 0 26.6
P-Site Similarity: 100 100 13.3 20 N.A. 86.6 N.A. N.A. 26.6 86.6 26.6 20 N.A. 20 40 20 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 28 24.4
Protein Similarity: N.A. N.A. N.A. N.A. 42.3 35.5
P-Site Identity: N.A. N.A. N.A. N.A. 0 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 40 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 20 7 14 0 7 7 14 0 7 0 7 7 7 % A
% Cys: 0 0 0 0 7 0 7 0 0 0 0 0 0 7 0 % C
% Asp: 7 0 14 7 0 7 34 0 7 27 0 0 0 7 0 % D
% Glu: 0 7 7 27 0 0 0 7 0 7 7 34 14 0 7 % E
% Phe: 7 7 0 0 7 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 7 0 14 0 7 0 7 20 0 0 0 7 0 0 % G
% His: 0 7 7 0 0 7 0 0 0 0 0 0 0 14 0 % H
% Ile: 14 0 0 0 0 0 7 0 7 14 0 14 0 0 7 % I
% Lys: 34 14 0 20 7 7 0 0 0 7 34 20 54 27 0 % K
% Leu: 7 0 0 0 0 0 0 0 0 0 14 0 0 0 0 % L
% Met: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 7 14 14 7 14 14 7 14 7 7 0 7 % N
% Pro: 14 7 0 7 14 0 14 7 0 14 7 7 7 7 0 % P
% Gln: 0 14 0 0 7 7 0 0 7 0 7 0 0 7 40 % Q
% Arg: 0 0 0 0 0 0 0 0 14 7 7 0 7 7 20 % R
% Ser: 0 27 14 14 20 20 7 40 14 14 7 7 0 14 7 % S
% Thr: 14 7 7 0 0 0 0 14 7 0 0 7 0 0 0 % T
% Val: 0 0 0 0 7 27 14 7 0 0 0 7 0 7 0 % V
% Trp: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 27 0 7 0 7 0 0 7 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _